Antiestrogen Powder Raloxifene HCL

Product Name: Raloxifene HCL
CAS: 82640-04-8
MF: C28H28ClNO4S
MW: 510.05
Assay: 99%
Grade: Pharmaceutical Grade
Appearance: Light Yellow Powder
Usage: Pharmaceutical Raw Materials

Raloxifene HCL is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.

Raloxifene is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.

Raloxifene is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.

Raloxifene may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.

Antiestrogen Powder Toremifene Citrate

Product Name: Toremifene Citrate
Synonyms: Fareston
CAS: 89778-27-8
MF: C26H28ClNO.C6H8O7
MW: 598.09
Assay: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Melting Point: 158-164 dec.
Boiling Point: 535.1 dec. at 760 mmHg
Density: 1.045g/cm3
Refractive Index: 1,416-1,418

Toremifene Citrate Effect

Toremifene citrate is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body. Licensed in the United States under the brand name Fareston, toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer. It is also being evaluated for prevention of prostate cancer under the brand name Acapodene.

It has already been covered that Toremifene is a SERM, and serves to block Estrogen at various receptor sites in certain tissues within the body (breast tissue in particular). As a layman explanation, Toremifene pretends to be a 'fake' Estrogen that occupies Estrogen receptors within breast tissue. With these receptors occupied by Toremifene, real Estrogen cannot perform their jobs there. Toremifene does not reduce total blood plasma levels of Estrogen. In addition to being antagonistic to Estrogen receptors in breast tissue, it is also antagonistic to Estrogen at the hypothalamus gland (this essentially 'tricks' the hypothalamus into thinking there is little or no circulating Estrogen levels in the body, causing it to increase its manufacture of Testosterone so that it can utilize aromatization to restore these levels.

Toremifene Citrate exerts its effects by antagonizing the estrogen receptor in some tissues, and agonizing it in others. In this way, certain estrogenic pathways are activated and others are blockaded. It seems to exert estrogenic effects on blood lipids, reducing LDL and total cholesterol, as well as estrogenic effects on bone, improving density. It would also appear to exert anti-estrogenic effects in breast tissue, displacing the traditional effects of estrogen, effectively helping prevent breast cancer in postmenopausal women.

Fareston Administration

In the fight against breast cancer, standard Fareston doses will normally be 60mg per day. The total duration of use is unpredictable and will be based on patient need. It's not uncommon for treatment to last a year or two and then AI's to be added if needed. Once the cancer is in remission, compounds like Fareston are commonly used to support the improved state.

For the anabolic steroid user combating gynecomastia, standard Fareston doses will fall in the 30-60mg per day range and will work very well for most men. If this is not enough protection, while you could try increasing the dose your best bet would be to move to AI use. You will find Fareston works very well in combating gynecomastia due to the use of any testosterone, Dianabol and Anadrol. You will also find it works well with Equipoise and Deca Durabolin. However, as Deca Durabolin is also a progestin, men who are very sensitive to that hormone may need an AI. The same can be said of the Trenbolone hormone. Trenbolone does not aromatize, but it is a progestin. Further, the use of an aromatizing steroid with a compound like Trenbolone can increase the risk of gynecomastia in some men. While many will not need gynecomastia protection due to progestins and will get by with SERM's to combat aromatase, some sensitive men will need an AI. Regardless, if Fareston works for you it will cover the entire breadth of the cycle from start to finish.

Antiestrogen Powder Tamoxifen Citrate

Product Name: Tamoxifen Citrate
Alias: Tamoxifen,Nolvadex,Tamofen
CAS: 54965-24-1
EINECS: 259-415-2
MF: C26H29NO.C6H8O7
MW: 563.64
Assay: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Melting Point: 140-144 dec.

PCT Purpose

Tamoxifen Citrate and Clomifene Citrate are two of the most popular Selective Estrogen Receptor Modulators (SERMs) in the world and part of the supplemental plan for many performance enhancing athletes. More athletes buy Nolvadex for PCT purposes than any other purpose; in-fact, more performance enhancers buy Nolvadex for their PCT use than any other medication available.

In-fact, more performance enhancers buy Nolvadex for their PCT use than any other medication available. As you understand the purpose of the PCT period is to stimulate natural testosterone production after a cycle of anabolic steroids has been discontinued; this is necessary as anabolic steroids suppress natural testosterone production. Further, beyond testosterone stimulation this is the period when we begin normalizing our body but in the case of Tamoxifen Citrate it is testosterone production we are concerned with here.

Gynecomastia(male breast enlargement) is one of the most worrisome side-effects that can occur due to anabolic androgenic steroid use, fortunately you can buy Nolvadex and combat this effect; no, Tamoxifen Citrate will not reduce the amount of estrogen in your body but it will prevent a large portion of it from binding and this provides protectio.

Nolvadex Dosage

The average Nolvadex dosage can vary quite dramatically depending the purpose of use as well as whos using it. In most cases the compound comprised of Tamoxifen Citrate will be used for on cycle side-effect prevention, Post Cycle Therapy (PCT) and by females for a testosterone boosting effect or as part of a physique competition preparation. In any case the average Nolvadex dosage will range from 10mg to 40mg and in most cases never exceed this mark.

For most women the most common Nolvadex dosage will be at 10mg per day with very few ever exceeding 20mg per day and most will never need this much.

The purpose of use during PCT is simple; to stimulate natural testosterone production that has been suppressed due to anabolic steroid use and more than likely tremendously so. For most men daily therapy will begin at 40mg per day, eventually dropping to 20mg per day until use is discontinued. The average man will need at least 4 weeks of total therapy with many men needing 6 total weeks if their steroid cycle was long and suppressive in nature. However long your PCT plan is a Nolvadex dosage of 40mg per day for the first half of the plan followed by a 20mg every day the final weeks will suffice.

Antiestrogen Powder Clomifene Citrate

Product Name: Clomifene Citrate
Alias: Serophene,Clomid,Pergotime,Clomphid,Clomiphene,Androxal,Clomiphene Citrate
CAS: 50-41-9
EINECS: 200-035-3
MF: C32H36ClNO8
MW: 598.08
Assay: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials

Clomifene Effect

Clomiphene Citrate, or Clomid, is a SERM (selective estrogen receptor modulator), so it's in the same grouping as tamoxifen (nolvadex). It is the most widely prescribed drug for ovulation induction, which is useful for those who are infertile.

Male bodybuilders who cycle anabolic androgenic steroids (AAS) have found that the same mechanisms of increased LH (luteinizing hormone) can be taken advantage of to increase total testosterone levels. This is why clomid is popular in post cycle therapy (PCT) among those who cycle anabolic steroids. Since clomid has ability to bind to the estrogen receptors, much like nolvadex, in male users who run estrogenic compounds such as testosterone, dianabol, and deca durabolin, it can be used as gynecomastia treatment (anti-gyno). However, clomid is a fairly weak anti-gyno aid, and is rarely used for that purpose. Due to its ability to boost testosterone levels, it has been put on the WADA (world anti-doping agency) list of illegal doping agents in sport.

PCT

When a steroid user runs a cycle their HPTA becomes suppressed; as a result, their bodies LH and FSH drop to almost zero (0) and their body stops producing testosterone. Their testicles typically will shrink as the body realizes there are too many hormones present and it's not necessary to produce more. So, when you come off a cycle it's important to run a PCT (post cycle therapy) to help recover the body's HPTA.

Clomid stimulates the hypophysis to release more gonadotropins. Gonadotropins are protein hormones that are secreted by gonadotrope cells of the pituitary gland and stimulate faster and higher release of follicle stimulating hormone (FSH) and luteinizing hormone (LH). When an increase in gonadotropins happens, the rise in LH will spike up the total testosterone levels allowing the user to artificially maintain high testosterone levels until their own body is able to recover, thus maintaining gains.

Clomid Dosage

If you're going to put it into your body from medicine to hormones or in this case a SERM you are going to want to know the proper dose; after all, without this information it's unlikely you're going to be able to use it correctly. Like many things a Clomid dosage can vary quite dramatically but one thing is for certain the average Clomid dosage among many performance enhancers is far too low. It is very common to see a Clomid dosage of 50mg per day for Post Cycle therapy (PCT) purposes and while there is a use for this dose during PCT it should be noted, 50mg of this SERM is about the equivalent of 10mg of Nolvadex.

Antiestrogen Powder Formestane

Product Name: Formestane
Alias: Lentaron
CAS: 566-48-3
MF: C19H26O3
MW: 302.4126
Assay: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Melting Point: 199-202 dec.

Formestane (lentaron, chemical name: 4-hydroxyandrostenedione) is a type I steroidal aromatase inhibitor (AI). It was developed for use in treatment of estrogen-receptor-positive breast cancer in post-menopausal women. For medical purposes, it is made in intramuscular depot form and injected. It is not used in oral form due to poor bioavailability, which makes the oral version inferior to aromasin, letrozole, and arimidex.

Decreasing SHBG

According to studies, formestane can lower SHBG up to 34%, which will increase free testosterone levels. SHBG (sex hormone binding globulin) is a protein that binds to sex steroids, and renders them inactive, for as long as SHBG is bound to them. There is a difference between 'free' testosterone, and 'bound' testosterone. Free testosterone is what matters, so lowering SHBG will increase 'free' testosterone. Higher testosterone means more strength, muscle mass, less body fat, better sense of well being, and libido.

Aromatase Inhibitor

Many anabolic steroids aromatize in the body into estrogen. The most common are deca durabolin, equipoise, testosterone, and dbol. If an AI is not used, estrogen will increase and potentially cause major problems with estrogenic side effects. The most common side effects of estrogen are gynecomastia (bitch tits), excessive water retention (moon face), high blood pressure (hypertension), and insomnia.

In addition, coming off cycle with estrogen levels that are too high can hinder recovery of the body's HPTA, causing gains on cycle to be lost. Formestane, while being used, will permanently disable the aromatase enzyme, so that it does not rebound after cycle. Other AI's, such as letrozole and arimidex will not stop estrogen rebound.

Formestane Dosage

The most common version of formestane sold was in a topical gel form and it was dosed at 100-200mgs per application. Users would apply it onto clean, dry skin and rub in thoroughly; usually on the thighs or upper arms. It took 1 to 5 minutes to dry.

The injectable version for both breast cancer purposes and bodybuilders is 125mgs twice per week or 250mgs once per week.

Antiestrogen Powder Exemestane

Product Name: Exemestane
Alias: Exemestan,Aromasin
CAS: 107868-30-4
MF: C20H24O2
MW: 296.40
Assay: 98%min
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials

Exemestane Effect

Exemestane is a suicidal aromatase inhibitor (AI), meaning it permanently disables the aromatase enzyme once it binds to it. In plain English, Exemestane will prevent the currently bound enzymes from rebounding, which is what separates this drug from letrozole or arimidex. When you use other AI's, they temporarily stop estrogen from aromatizing, but when you stop taking them those same enzymes can rebound causing what is known as 'estrogen rebound'. This explains why some anabolic steroid users experience gynecomastia (bitch tits) after cycle when using other AI's. Studies on breast cancer patients have shown Exemestane reduced estrogen levels up to 85%.

Athletes commonly buy Exemestane to aid in their performance enhancement in conjunction with anabolic steroids. As an aromatase inhibitor Exemestane reduces the amount of estrogen in the body and this is precisely the reason any athlete will buy Exemestane. Make no mistake, Estrogen is essential to our overall well-being but this hormone is also damaging to a physique when levels become too high.When our estrogen levels are too high we will have difficulty in maintaining a lean and hard physique and if were using anabolic steroids a host of negative side-effects can rear their heads.This is why many steroid users buy Exemestane and with proper use they eliminate the potential problems associated with estrogen build up.

Exemestane Dosage

This is dependent on the individual and, also, the amount of aromatizing compounds the person is running. Generally, a good starting dose is 12.5mg ED (every day) or 25mg EOD (every other day). The user must utilize blood work to see how their body is reacting at the starting dosage they choose and then adjust as needed. Experienced anabolic steroid users will usually find a dose they like and stick to it with no problems. As I said already, if you start noticing joint issues then the dose should be lowered; on the other hand, if you start noticing any estrogen related sides, such as puffy or sensitive breasts or water retention, it's time to increase the dosage.

Antiestrogen Powder Letrozole

Product Name: Letrozole
Alias: Femara,Lelrozol,Trozet,Letroz,Lelroz,Letrozolex
CAS: 112809-51-5
MF: C17H11N5
MW: 285.3
Purity: 98%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials

Letrozole Profile

Letrozoles are non suicidal Aromatase Inhibitors, belonging to the third generation of aromatase inhibitors. They are administered orally and hold the approval of the Food and Drug Administration of the United States (FDA) for use in treating two particular kinds of breast cancer. One is the case when hormone receptor positive breast cancer develops locally or is contracted through metastatis. The other is a similar case but when the cancer is of the estrogen receptor unknown category.

The estrogen receptor unknown category refers to those breast cancer conditions where the role of estrogens can not be determined with certainty. In these cases, it is impossible to predict if estrogen caused the cancer in the first place or if it would complicate and worsen the cancer further. Letrozoles are used in the treatment of such cancer conditions in post menopausal women. It is however rare that Letrozole be required for treating the post menopausal estrogen receptor unknown cancer, first-line. In most cases, it is used only after the usual first-line treatments using Selective Estrogen Receptor Modulator drugs like the Nolvadex have failed to show any positive effects.

Letrozole Effect

Letrozole is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from Letrozole include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system.

Dosages And Half Life

The half life is approximately 2-4 days. Dosages vary quite a bit, 0.25mg up to 1mg every day or every other day is a good starting dose. It's best to be conservative with the dosage because if you overdose the sides can be harsh.

Antiestrogen Powder Anastrozole

Product Name: Anastrozole
Alias: Armotraz,Arimidex,Anastrol,Egistrozol,Anastrozolo
CAS: 120511-73-1
MF: C17H19N5
MW: 293.37
Assay: 98%~102%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Pharmaceutical Raw Materials
Active Life Cycle: 46 Hours

Anastrozole Effect

Anastrozole can be referred to as an aromatase inhibitor which helps prevent estrogen production in females. Research has shown that the estrogen hormone is responsible for the creation of breast cancer tumors in women. Anastrozole is the drug administered to intercept the enzyme aromatase, which is a substance that assists the body tissues in producing estrogen. Anastrozole is a popular drug in the battle against breast cancer. It is by and large, a hormonal treatment which can prevent the recurrence of breast cancer. Anastrozole, also known as Anastrozole is not a steroid.

Anastrozole is known to have diminished estrogen way too much in some patients. This is why blood tests or salivary tests are recommended after a week of usage to determine whether the dosage is appropriate.

Anastrozole tends to work quite differently than the traditional anti-estrogens. Anti-estrogens like Clomid or Nolvadex tend to intercept estrogen receptors in certain tissues while activating them in others. Meanwhile, Anastrozole directly intercepts the enzyme aromatase. When a patient has been recommended the use of Anastrozole, Clomid use along with is unnecessary. Doing so may have some benefits.

Anastrozole is generally used for all stages and forms of breast cancer which are classified to be estrogen receptor positive. In case the patient has estrogen receptor negative or triple negative cancer, the usage of Anastrozole is unlikely to help.

How does Anastrozole work?

Anastrozole generally works by blocking the aromatoze enzymes, facilitating the decrease in the production of estrogen in the human body. With the decrease in production of Anastrozole, the risk of exposure to breast cancer is eliminated. This procedure of treating breast cancer is known as hormonal therapy.

Anastrozole Dosages

Dosages of Anastrozole will vary from person to person. This is why blood work is essential to finding the perfect balance. One should start out at half a mg every other day and adjust as needed for the cycle. Some AAS users will not use an AI at first but they will have it on hand just in case. This isn't always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize (steroids turning into estrogen), taking Anastrozole at this point would be like trying to stop a car already in motion.

General dosages for men: 0.5mgs per day or every other day. Remember, it's steroid dose dependent.